Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420706 | 0.90 | BRAF (0.37) | BRAFSLC22A12MRGPRX1CA1CA2 | |
| SCHEMBL16479655 | 0.85 | SSTR4 (0.36) | BRAFSLC22A12MRGPRX1PTGES2NPC1 | |
| SCHEMBL2413234 | 0.83 | PTGES2 (0.42) | BRAFCA1CA2PTGES2 | |
| SCHEMBL618976 | 0.83 | SSTR4 (0.39) | BRAFSLC22A12MRGPRX1PDE10A | |
| SCHEMBL15972868 | 0.83 | BRAF (0.37) | BRAFMRGPRX1NPC1RAB9A | |
| SCHEMBL2415372 | 0.82 | MRGPRX1 (0.34) | BRAFSLC22A12MRGPRX1NPC1RAB9A | |
| SCHEMBL12219979 | 0.81 | SSTR4 (0.38) | BRAFMRGPRX1NPC1RAB9A | |
| SCHEMBL15990258 | 0.81 | AAK1 (0.37) | BRAFMRGPRX1CA1CA2 | |
| SCHEMBL618909 | 0.81 | BRAF (0.41) | BRAFMRGPRX1CA1CA2PTGES2 | |
| SCHEMBL17363082 | 0.80 | MRGPRX1 (0.33) | BRAFSLC22A12MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |