Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CALML3 | P27482 | 1/20 | 0.44 |
| ▸ | SDHA | P31040 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237032 | 0.93 | F10 (0.52) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6239389 | 0.93 | F10 (0.56) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6237098 | 0.93 | F10 (0.56) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6233491 | 0.92 | F10 (0.55) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6235612 | 0.91 | F10 (0.53) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6235614 | 0.91 | F10 (0.53) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6236038 | 0.88 | F10 (0.53) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6236028 | 0.88 | F10 (0.53) | F10MAOBF2ITGB3ITGA2B | |
| SCHEMBL6260349 | 0.85 | F10 (0.48) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL6237156 | 0.85 | KDM4E (0.47) | F10MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | disclosed |