Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.57 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.43 |
| ▸ | F9 | P00740 | 2/20 | 0.43 |
| ▸ | PROC | P04070 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CFH | P08603 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838861 | 0.89 | F10 (0.54) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3830430 | 0.83 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6245380 | 0.78 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6839520 | 0.78 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6838928 | 0.78 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6839419 | 0.76 | F10 (0.78) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6838432 | 0.76 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6240978 | 0.76 | F10 (0.77) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4681061 | 0.75 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6238878 | 0.75 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539686-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024679-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |