Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241344 | 0.90 | S1PR1 (0.47) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6236947 | 0.90 | S1PR1 (0.47) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6237747 | 0.90 | S1PR1 (0.50) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6258547 | 0.87 | S1PR1 (0.47) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6255594 | 0.86 | HPGD (0.42) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6262128 | 0.85 | S1PR1 (0.45) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6257860 | 0.85 | S1PR1 (0.45) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL6255296 | 0.83 | S1PR1 (0.50) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL6240287 | 0.82 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5FAAH | |
| SCHEMBL6241770 | 0.82 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |