Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 20/20 | 0.64 |
| ▸ | NR1H2 | P55055 | 19/20 | 0.64 |
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | VHL | P40337 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239641 | 1.00 | NR1H3 (0.64) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL22592767 | 0.88 | NR1H3 (0.61) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL3975467 | 0.85 | NR1H3 (0.64) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4949526 | 0.84 | NR1H3 (0.64) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4949536 | 0.84 | NR1H3 (0.64) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4948170 | 0.84 | NR1H3 (0.66) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4950044 | 0.80 | NR1H3 (0.57) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4949862 | 0.80 | NR1H3 (0.79) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL30198272 | 0.80 | NR1H3 (0.69) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4950057 | 0.80 | NR1H3 (0.57) | NR1H3NR1H2RXRAMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023196-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |