SCHEMBL6239693

SCHEMBL6239693

COc1cc2c(cc1OC)C=C[CH]2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 4/20 0.36
CA2 P00918 3/20 0.36
ACHE P22303 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
KDM4E B2RXH2 3/20 0.34
GLA P06280 2/20 0.34
MAOA P21397 2/20 0.34
BRD4 O60885 3/20 0.34
CCL2 P13500 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3847079 0.70
SCHEMBL815828 0.69
SCHEMBL815579 0.69
SCHEMBL22982710 0.69
SCHEMBL28152728 0.69
SCHEMBL11170689 0.68 BRD4 (0.49) CYP3A4MAPTALDH1A1CA2ACHE
SCHEMBL1276533 0.67 CYP3A4 (0.59) CYP3A4MAPTALDH1A1CA2ACHE
SCHEMBL7445614 0.66 CYP3A4 (0.31) CYP3A4MAPT
SCHEMBL7839529 0.65 CYP3A4 (0.34) CYP3A4MAPTALDH1A1CA2ACHE
SCHEMBL5009168 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1130383-C Hydrogenizing method for conjugate diene polymer and its adaptive catalyst composition SHELL INT RESEARCH (NL) 2003-12-10 CN claimed
EP-0810231-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2000-01-19 EP claimed
US-5886107-A USING TITANIUM CATALYST, ALKALI METAL HYDRIDE SHELL OIL COMPANY (US) 1999-03-23 US claimed
EP-0810231-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-12-03 EP claimed
CN-1163275-A Hydrogenizing method for conjugate diene polymer and its adaptive catalyst composition SHELL INT RESEARCH (NL) 1997-10-29 CN claimed
CN-1223627-C Resin composition containing ethylene-like polymer, and its producing method MARUZEN PETROCHEM CO LTD (JP) 2005-10-19 CN disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed
CN-1130383-C Hydrogenizing method for conjugate diene polymer and its adaptive catalyst composition SHELL INT RESEARCH (NL) 2003-12-10 CN disclosed
CN-1405224-A Resin composition containing ethylene-like polymer, and its producing method MARUZEN PETROCHEM CO LTD (JP) 2003-03-26 CN disclosed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP disclosed
EP-0810231-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2000-01-19 EP disclosed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US disclosed
US-5886107-A USING TITANIUM CATALYST, ALKALI METAL HYDRIDE SHELL OIL COMPANY (US) 1999-03-23 US disclosed
EP-0810231-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-12-03 EP disclosed
CN-1163275-A Hydrogenizing method for conjugate diene polymer and its adaptive catalyst composition SHELL INT RESEARCH (NL) 1997-10-29 CN disclosed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP disclosed