Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.83 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.83 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL5569329 | 1.00 | — | — | |
| Glycine SCHEMBL8585762 | 1.00 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL20295 | 1.00 | — | — | |
| Glycine SCHEMBL21879657 | 1.00 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL6853447 | 1.00 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL6511637 | 0.96 | — | — | |
| Glycine SCHEMBL27902160 | 0.96 | — | — | |
| Glycine SCHEMBL28163026 | 0.96 | — | — | |
| Glycine SCHEMBL27533089 | 0.96 | GLRA1 (0.77) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL27902232 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012514-B1 | Compositions containing lignocellulosic biomass residues, polymer composites made therefrom, and methods of making lignocellulosic biomass residues and polymer composites containing them | PLANTOON TECHNOLOGIES KFT. (HU) | 2024-06-18 | — | — | US | disclosed |
| EP-4326804-A1 | PROCESS FOR PREPARING COATED SHAPED BODIES AND THEIR USE | BASF SE (DE) | 2024-02-28 | — | — | EP | disclosed |
| EP-4313319-A1 | PROCESS FOR THE COSMETIC TREATMENT OF BRAIDED HAIR WITH A COMPOSITION COMPRISING A THICKENING POLYMER, A DERIVATIVE OF MENTHOL AND A PARTICULAR NON-IONIC SURFACTANT | L'OREAL (FR) | 2024-02-07 | — | — | EP | disclosed |
| US-11643561-B2 | Process for the preparation of metallic nano-particle layers and their use for decorative or security elements | BASF SE | 2023-05-09 | — | — | US | disclosed |
| EP-4110767-A1 | ADDITIVE MIXTURES FOR RHEOLOGY MODIFICATION OF POLYMERS | BASF SE (DE) | 2023-01-04 | — | — | EP | disclosed |
| EP-4110862-A1 | POLYOLEFIN COMPOSITIONS | BASF SE (DE) | 2023-01-04 | — | — | EP | disclosed |
| EP-4010392-A1 | THERMOPLASTIC POLYURETHANE CONTAINING A POLYSILOXANE CAPROLACTONE POLYOL | Lubrizol Advanced Materials, Inc. (US) | 2022-06-15 | — | — | EP | disclosed |
| US-11274219-B2 | Surface functionalized titanium dioxide nanoparticles | BASF SE (DE) | 2022-03-15 | — | — | US | disclosed |
| EP-3917491-A1 | COSMETIC COMPOSITION OF LIQUID CRYSTAL LIPID PARTICLES FOR PERSONAL CARE APPLICATIONS | BASF SE (DE) | 2021-12-08 | — | — | EP | disclosed |
| US-20210086545-A1 | PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT (EMBOSSED) FILMS ON FLEXIBLE SUBSTRATES | BASF SE (DE) | 2021-03-25 | — | — | US | disclosed |
| EP-0476110-A4 | COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM | — | 1992-11-25 | — | — | EP | disclosed |
| EP-0476110-A1 | COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM | ESSENTIAL DENTAL SYSTEMS, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1991015183-A1 | COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM | ESSENTIAL DENTAL SYSTEMS, INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0426192-A2 | Light-sensitive material comprising polymerizable layer and light-sensitive layer provided on support | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |
| WO-1991002022-A1 | ACRYLIC RESIN COMPOSITION | EDWARDS BILL R (US) | 1991-02-21 | — | — | WO | disclosed |
| EP-0323711-A1 | Electrode with hydrogel matrix for medical use | LecTec Corporation (US) | 1989-07-12 | — | — | EP | disclosed |
| EP-0270751-A2 | Electrolyte solution for use in electrodes for measuring ions and method for its manufacture | HORIBA, LTD. (JP) | 1988-06-15 | — | — | EP | disclosed |
| EP-0227819-A4 | A PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF POLY(ALKYLENE CARBONATE) POLYOLS. | DOW CHEMICAL CO (US) | 1988-02-08 | — | — | EP | disclosed |
| EP-0227819-A1 | A PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF POLY(ALKYLENE CARBONATE) POLYOLS | THE DOW CHEMICAL COMPANY (US) | 1987-07-08 | — | — | EP | disclosed |
| WO-1987000185-A1 | A PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF POLY(ALKYLENE CARBONATE) POLYOLS | THE DOW CHEMICAL COMPANY (US) | 1987-01-15 | — | — | WO | disclosed |