Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239949 | 1.00 | HDAC1 (0.71) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6237618 | 0.94 | HDAC1 (0.66) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6237611 | 0.94 | HDAC1 (0.66) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6244200 | 0.88 | HDAC1 (0.69) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6241988 | 0.88 | HDAC1 (0.69) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6237456 | 0.88 | HDAC1 (0.67) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6239623 | 0.88 | HDAC1 (0.67) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6239617 | 0.85 | HDAC1 (0.79) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6239624 | 0.85 | HDAC1 (0.79) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL6237614 | 0.85 | HDAC1 (0.62) | HDAC1HDAC4HDAC6HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | claimed |
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |