Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608246 | 0.86 | BCL9 (0.55) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL29769253 | 0.86 | BCL9 (0.55) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL9168629 | 0.86 | BCL9 (0.55) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL9551670 | 0.86 | F2 (0.56) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL7069631 | 0.85 | BCL9 (0.56) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL19203693 | 0.83 | BCL9 (0.65) | BCL9CTNNB1EGFRERBB2KMT2A | |
| SCHEMBL27543803 | 0.83 | BCL9 (0.57) | F2BCL9CTNNB1EGFRERBB2 | |
| SCHEMBL5524169 | 0.83 | F2 (0.58) | F2BCL9CTNNB1KMT2AALOX5 | |
| SCHEMBL4849025 | 0.80 | BCL9 (0.68) | F2BCL9CTNNB1KMT2AALOX5 | |
| SCHEMBL27498672 | 0.80 | F2 (0.48) | F2BCL9CTNNB1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014528-A1 | STRAIGHT-CHAIN AND BRANCHED-CHAIN LIPID COMPOUNDS AS SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2, ANTI-INFLAMMATORY AGENTS, AND ANTI-CANCER AGENTS | YANG ZHENHUA (US) | 2005-02-17 | — | — | WO | disclosed |