Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458619 | 0.88 | ADRB3 (0.50) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL9316827 | 0.86 | BACE1 (0.46) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL7120076 | 0.85 | BACE1 (0.43) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL7120069 | 0.85 | BACE1 (0.43) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL4459901 | 0.83 | ADRB3 (0.43) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL4459899 | 0.83 | ADRB3 (0.43) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL9317592 | 0.83 | ADRB3 (0.62) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL9316986 | 0.82 | ADRB3 (0.51) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL6680776 | 0.81 | BACE1 (0.40) | ADRB3ADRB2ADRB1CYP2D6ADRA1D | |
| SCHEMBL6540398 | 0.79 | ADRB3 (0.49) | ADRB3ADRB2ADRB1CYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |