Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 10/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414503 | 0.91 | MCHR1 (0.50) | MCHR1IKBKBCHUK | |
| SCHEMBL620761 | 0.88 | IKBKB (0.50) | IKBKBCHUKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3813434 | 0.81 | MCHR1 (0.42) | MCHR1IKBKBCTSS | |
| SCHEMBL620112 | 0.79 | TEAD1 (0.43) | MCHR1CTSSCTSK | |
| SCHEMBL29530213 | 0.79 | KDM4E (0.48) | AVPR2AVPR1ACTSSSLC6A2SLC6A4 | |
| SCHEMBL2413474 | 0.78 | IKBKB (0.44) | MCHR1IKBKBCHUK | |
| SCHEMBL619309 | 0.76 | IKBKB (0.50) | IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL621380 | 0.75 | MCHR1 (0.51) | MCHR1IKBKBCHUK | |
| SCHEMBL620849 | 0.75 | MCHR1 (0.51) | MCHR1IKBKBCHUK | |
| SCHEMBL31670291 | 0.75 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |