Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048026 | 0.89 | HSD17B10 (0.59) | LMNAGAAMAPTTDP1HSD17B10 | |
| SCHEMBL25274668 | 0.87 | ESR1 (0.55) | LMNAGAAMAPTTDP1HSD17B10 | |
| SCHEMBL236488 | 0.85 | ESR1 (0.57) | MAPTTDP1HSD17B10MEN1KMT2A | |
| SCHEMBL29672387 | 0.85 | ESR1 (0.57) | MAPTTDP1HSD17B10MEN1KMT2A | |
| SCHEMBL237166 | 0.85 | ESR1 (0.57) | MAPTTDP1HSD17B10MEN1KMT2A | |
| SCHEMBL30155392 | 0.85 | KMT2A (0.61) | LMNAGAAMAPTTDP1HSD17B10 | |
| SCHEMBL30439313 | 0.85 | KMT2A (0.61) | LMNAGAAMAPTTDP1HSD17B10 | |
| SCHEMBL338523 | 0.85 | KMT2A (0.61) | LMNAGAAMAPTTDP1HSD17B10 | |
| SCHEMBL5045929 | 0.85 | CA12 (0.57) | LMNAGAAMAPTTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28481470 | 0.83 | KMT2A (0.59) | LMNAGAAMAPTTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005010202-A2 | PHENYL ACETIC ACID DERIVATIVES AS HEPATOCYTE NUCLEAR FACTOR 4α (HNF-4α) MODULATOR COMPOUNDS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005010202-A2 | PHENYL ACETIC ACID DERIVATIVES AS HEPATOCYTE NUCLEAR FACTOR 4α (HNF-4α) MODULATOR COMPOUNDS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |