Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.74 |
| ▸ | PPARA | Q07869 | 16/20 | 0.74 |
| ▸ | PPARG | P37231 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242977 | 0.91 | PPARD (0.61) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2167820 | 0.88 | PPARD (0.81) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6239835 | 0.87 | PPARD (0.66) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6236335 | 0.87 | PPARD (0.70) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6237463 | 0.86 | PPARD (0.63) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL29376887 | 0.85 | PPARD (1.00) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL29422488 | 0.85 | PPARD (1.00) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2064674 | 0.85 | PPARD (1.00) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL20482074 | 0.85 | PPARD (0.78) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6234859 | 0.84 | PPARD (0.59) | PPARDPPARAPPARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-06-08 | — | — | EP | claimed |