⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360974 | 1.00 | — | — | |
| SCHEMBL10296585 | 0.84 | — | — | |
| SCHEMBL12569212 | 0.74 | — | — | |
| SCHEMBL3626952 | 0.72 | — | — | |
| SCHEMBL12448905 | 0.71 | — | — | |
| SCHEMBL2044984 | 0.71 | — | — | |
| SCHEMBL257210 | 0.71 | — | — | |
| SCHEMBL4643763 | 0.69 | — | — | |
| SCHEMBL18561599 | 0.67 | — | — | |
| SCHEMBL4022348 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192399-A | Adding caustic compound and separating by low pressure distillation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-09 | — | — | US | claimed |
| JP-1203392-A | — | — | None | — | — | JP | disclosed |
| CN-111655681-B | Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases | 莱德克斯制药公共有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116751170-A | Method for directly preparing semi-hydrogenated nitrogen-containing aromatic heterocyclic compound from sugar | 浙江大学 | 2023-09-15 | — | — | CN | disclosed |
| US-10394083-B2 | Oriented film, polymer, and liquid crystal display device | SHARP KABUSHIKI KAISHA (JP) | 2019-08-27 | — | — | US | disclosed |
| US-20190049796-A1 | ORIENTED FILM, POLYMER, AND LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2019-02-14 | — | — | US | disclosed |
| US-9540370-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | ABBVIE DEUTSCHLAND GMBH & CO., KG. (DE) | 2017-01-10 | — | — | US | disclosed |
| US-20150274724-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-01 | — | — | US | disclosed |
| US-9090592-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20120172376-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2012-07-05 | — | — | US | disclosed |
| EP-1539686-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024679-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |
| EP-0453960-B1 | Sulfonylamino substituted bicyclyl hydroxamic acid derivatives | SHIONOGI & CO (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5137914-A | Vasodilation, anticoagulants, bronchodilator agents | SHIONOGI & CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0453960-A1 | Sulfonylamino substituted bicyclyl hydroxamic acid derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| JP-H01203392-A | NOVEL SPIROXAZINE COMPOUND | TORAY IND INC | 1989-08-16 | — | — | JP | disclosed |