Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583679 | 0.78 | IDO1 (0.53) | SYKIDO1ATMPPARAPPARG | |
| SCHEMBL6244523 | 0.76 | SYK (0.51) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL8240431 | 0.75 | ATM (0.61) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL13114024 | 0.75 | ATM (0.61) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL8242933 | 0.75 | ATM (0.61) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL20832961 | 0.74 | SYK (0.57) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL19295578 | 0.74 | SYK (0.57) | SYKIDO1ATMCTSSCTSK | |
| SCHEMBL13510821 | 0.74 | ATM (0.60) | SYKIDO1ATMPPARACTSS | |
| SCHEMBL13510756 | 0.74 | ATM (0.60) | SYKIDO1ATMPPARACTSS | |
| SCHEMBL7056648 | 0.74 | SYK (0.51) | SYKIDO1ATMPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118613-A2 | ANTIBACTERIAL AMIDE MACROCYCLES | AICURIS GMBH & CO.KG (DE) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005033129-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2005-04-14 | — | — | WO | disclosed |