Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244283 | 0.88 | MAPT (0.83) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6503866 | 0.87 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6245267 | 0.86 | MAPT (0.76) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6244997 | 0.85 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10018556 | 0.80 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13856442 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6263727 | 0.78 | HPSE (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4020386 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14096539 | 0.76 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6293914 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |