SCHEMBL6243997

SCHEMBL6243997

C=C1CCCCCCCC(=O)CCCCCCC1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.69
TRIM33 Q9UPN9 2/20 0.69
ALDH1A1 P00352 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064998 1.00 TRIM24 (0.69) TRIM24TRIM33ALDH1A1
SCHEMBL6244784 1.00 TRIM24 (0.69) TRIM24TRIM33ALDH1A1
Cyclohexanone SCHEMBL2487748 0.83
Cycloheptanone SCHEMBL28101629 0.83 TRIM24 (0.85) TRIM24TRIM33ALDH1A1
Cyclohexanone SCHEMBL3671904 0.83
SCHEMBL25380098 0.83 TRIM24 (1.00) TRIM24TRIM33ALDH1A1
SCHEMBL2221624 0.83 TRIM24 (0.38) TRIM24TRIM33ALDH1A1
SCHEMBL1635045 0.83
Cyclohexanone SCHEMBL713141 0.83
Cyclohexanone SCHEMBL3299 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313692-B1 NOVEL MACROCYCLIC KETONES SYMRISE GMBH & CO KG (DE) 2005-07-20 EP claimed
US-6815413-B2 SATURATED OR UNSATURATED CYCLOHEXADECANONES ARE GRAND FRAGRANCES WITH MUSCONE NOTE WITH WHICH PERFUMES WITH NEW ODOR NOTES CAN BE PREPARED SYMRISE GMBH & CO. KG (DE) 2004-11-09 US claimed
EP-1313692-A1 NOVEL MACROCYCLIC KETONES HAARMANN & REIMER GMBH (DE) 2003-05-28 EP claimed
US-20020055453-A1 Novel macrocyclic ketones SYMRISE GMBH & CO. KG (DE) 2002-05-09 US claimed
WO-2002012157-A1 NOVEL MACROCYCLIC KETONES HAARMANN & REIMER GMBH (DE) 2002-02-14 WO claimed
EP-1313692-B1 NOVEL MACROCYCLIC KETONES SYMRISE GMBH & CO KG (DE) 2005-07-20 EP disclosed
US-6815413-B2 SATURATED OR UNSATURATED CYCLOHEXADECANONES ARE GRAND FRAGRANCES WITH MUSCONE NOTE WITH WHICH PERFUMES WITH NEW ODOR NOTES CAN BE PREPARED SYMRISE GMBH & CO. KG (DE) 2004-11-09 US disclosed
EP-1313692-A1 NOVEL MACROCYCLIC KETONES HAARMANN & REIMER GMBH (DE) 2003-05-28 EP disclosed
US-20020055453-A1 Novel macrocyclic ketones SYMRISE GMBH & CO. KG (DE) 2002-05-09 US disclosed
WO-2002012157-A1 NOVEL MACROCYCLIC KETONES HAARMANN & REIMER GMBH (DE) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055453-A1 Novel macrocyclic ketones FASN, KCNK5, NOTUM TRIM24 2821/4885TRIM33 3212/4885ALDH1A1 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.