Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415695 | 0.97 | — | — | |
| SCHEMBL6563 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29994471 | 0.95 | — | — | |
| Bromide SCHEMBL29427044 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL243023 | 0.95 | — | — | |
| Bromide SCHEMBL119703 | 0.95 | — | — | |
| Bromide SCHEMBL1716492 | 0.93 | — | — | |
| Bromide SCHEMBL28224623 | 0.93 | — | — | |
| Pyridine SCHEMBL3056288 | 0.89 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL6472832 | 0.85 | SMN1; SMN2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000473-A2 | PENTAVALENT SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING STEREOSPECIFIC ALKYLPHOSPHONATES AND ARYLPHOSPHONATES | RES CORP TECHNOLOGIES INC (US) | 1994-01-06 | — | — | WO | claimed |
| US-20050287619-A1 | Method and reagent for measuring cholesterol in high-density lipoproteins | KYOWA MEDEX CO., LTD. (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1555327-A1 | METHOD AND REAGENT FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEINS | Kyowa Medex Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |