Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | HPGD | P15428 | 5/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | ALB | P02768 | 1/20 | 0.81 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.81 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | TUBB | P07437 | 1/20 | 0.79 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.79 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.79 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.79 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.79 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.79 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.79 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.79 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.79 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.79 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desmethyl-Ofloxacin SCHEMBL30542144 | 1.00 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| N-Desmethyl Levofloxacin SCHEMBL30306092 | 1.00 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| N-Desmethyl Levofloxacin SCHEMBL5021672 | 1.00 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| N-Desmethyl Levofloxacin SCHEMBL20577525 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Desmethyl-Ofloxacin SCHEMBL6247374 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Hydrochloric Acid SCHEMBL11075292 | 0.95 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL26197440 | 0.91 | KDM4E (0.85) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL11198681 | 0.91 | KDM4E (0.85) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL4545209 | 0.90 | KDM4E (0.84) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10931342 | 0.90 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115586264-B | Non-targeted screening method for veterinary drugs and metabolites thereof in milk | 中国科学院大连化学物理研究所 | 2024-11-12 | — | — | CN | disclosed |
| CN-116831986-A | Levofloxacin sodium chloride injection and preparation method thereof | 成都医路康医学技术服务有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| US-20140199391-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | API GENESIS, LLC (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | VYMED CORPORATION (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | VYMED CORPORATION (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | VYMED CORPORATION (US) | 2014-03-13 | — | — | US | disclosed |
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |
| EP-1406619-A4 | ANTIVIRAL AND ANTIMICROBIAL GUANIDINE OR BIGUANIDINE DERIVATIVES | SHETTY B VITHAL (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040132993-A1 | Antiviral and antimicrobial guanidine or biguanidine derivatives | SHETTY B VITHAL (US) | 2004-07-08 | — | — | US | disclosed |
| US-5637580-A | ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5491139-A | Antimicrobial quinolonyl lactams | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5387748-A | Antimicrobial dithiocarbamoyl quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0489733-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1990012799-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1990-11-01 | — | — | WO | disclosed |
| EP-0366193-A2 | Novel antimicrobial quinolonyl lactams | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0047005-B1 | BENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4382892-A | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0047005-A1 | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140199391-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | ABCG2, CYP2F1, LSS | KDM4E 2079/4885ALDH1A1 1920/4885HPGD 244/4885 |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | GDA, GMPS, GANC | KDM4E 2392/4885ALDH1A1 2165/4885HPGD 968/4885 |
| US-20040132993-A1 | Antiviral and antimicrobial guanidine or biguanidine derivatives | GMPS, GDA, GANC | KDM4E 2140/4885ALDH1A1 2918/4885HPGD 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.