Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.51 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247838 | 0.89 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3QSOX1 | |
| SCHEMBL6247516 | 0.84 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3QSOX1 | |
| Hydrochloric Acid SCHEMBL6248618 | 0.82 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6249261 | 0.81 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3QSOX1 | |
| SCHEMBL3364462 | 0.81 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3QSOX1 | |
| SCHEMBL3362492 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3QSOX1 | |
| Hydrochloric Acid SCHEMBL6250584 | 0.81 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6250587 | 0.81 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6250581 | 0.81 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6248601 | 0.79 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3QSOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157002-B1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-08-10 | — | — | EP | disclosed |