Biphenyl-4-Amine

Biphenyl-4-Amine

SCHEMBL62469

Nc1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
TAAR1 Q96RJ0 3/20 1.00
HSD17B10 Q99714 2/20 1.00
ALDH1A1 P00352 7/20 0.73
TP53 P04637 1/20 0.73
MAPT P10636 6/20 0.62
RAB9A P51151 3/20 0.62
NPC1 O15118 2/20 0.62
HPGD P15428 2/20 0.62
KDM4E B2RXH2 2/20 0.62
GLA P06280 1/20 0.62
ALOX15 P16050 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
TSHR P16473 1/20 0.62
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
MAOA P21397 4/20 0.57
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl-4-Amine SCHEMBL27682012 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL282830 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Benzidine SCHEMBL28050418 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Benzidine SCHEMBL308333 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Biphenyl-4-Amine SCHEMBL20296849 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL24524183 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Benzidine SCHEMBL29002343 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Biphenyl-4-Amine SCHEMBL15921057 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL21392391 1.00 CYP3A4 (1.00) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Biphenyl-4-Amine SCHEMBL28973472 0.97 CYP3A4 (0.94) CYP3A4TDP1TAAR1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11452 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903137-B Butyl tin-cycloiridium phenanthroline complex with AIE characteristics and preparation method and application thereof 曲阜师范大学 2026-05-22 CN claimed
WO-2026097199-A1 SINTERABLE BONDING MATERIAL AND SEMICONDUCTOR DEVICE USING THE SAME HENKEL AG & CO. KGAA (DE) 2026-05-15 WO claimed
US-12575601-B2 Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols MAGI'S LAB SRL (IT) 2026-03-17 US claimed
US-12544025-B2 Determining a biological tissue structural marker for diagnosis of a disease Arion Diagnostics, Inc. (US) 2026-02-10 US claimed
US-20260015471-A1 METHOD FOR PREPARING CONTROLLABLY CROSS-LINKED GRAPHENE-MODIFIED NATURAL RUBBER BASED ON AQUEOUS PHASE SYNERGISTIC AGGREGATING PRECIPITATING PROCESS UNIV NORTH CHINA (CN) 2026-01-15 US claimed
US-20250340704-A1 METHOD FOR PREPARING DUALLY-BONDED GRAPHENE OXIDE/NATURAL RUBBER COMPOSITE BASED ON HIGH-MOLECULAR-WEIGHT CATIONIC POLYMER UNIV NORTH CHINA (CN) 2025-11-06 US claimed
US-12359030-B2 Method for preparing uniformly-cured solid loading tires from high-modulus graphene oxide/natural rubber composite NORTH UNIVERSITY OF CHINA (CN) 2025-07-15 US claimed
WO-2025129352-A1 METHOD AND SYSTEM FOR BIOMARKER DETECTION EKIDNA SENSING INC. (CA) 2025-06-26 WO claimed
US-20250198641-A1 INDOOR AIR CLEANING SYSTEM MICROJET TECHNOLOGY CO., LTD. (TW) 2025-06-19 US claimed
EP-4571207-A1 INDOOR AIR CLEANING SYSTEM Microjet Technology Co., Ltd. (TW) 2025-06-18 EP claimed
US-5260388-A Reacting aromatic diamine with tetracarboxylic anhydride in presence of aromatic dicarboxylic anhydride or monoamine, imidizing; low dielectric characteristics; electronics MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-09 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO claimed
EP-0315479-B1 PROCESS FOR PREPARING POLYIMIDE AND COMPOSITE MATERIAL THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-04-07 EP claimed
US-5013817-A Monoamine reactant, melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US claimed
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP claimed
EP-0353460-A2 Membranes for solid phase protein sequencing MILLIPORE CORPORATION (US) 1990-02-07 EP claimed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP claimed