Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6247751

S.S=C(S)NCCNC(=S)S.[Mn]

nearest known ligand 0.60

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.60
ALDH1A1 P00352 2/20 0.60
HPGD P15428 2/20 0.60
ALOX15 P16050 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 1/20 0.60
THRB P10828 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10931171 0.97 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL9420257 0.97 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9
Hydrogen Sulfide SCHEMBL27316685 0.97 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL1157739 0.93 HSD17B10 (0.60) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL7923883 0.93 HSD17B10 (0.67) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL83488 0.93 HSD17B10 (0.67) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL28007458 0.90 HSD17B10 (0.57) HSD17B10ALDH1A1HPGDALOX15CYP2C9
SCHEMBL30958360 0.90 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9
Ammonia Solution, Strong SCHEMBL415941 0.90 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9
Ammonia Solution, Strong SCHEMBL9244428 0.90 HSD17B10 (0.63) HSD17B10ALDH1A1HPGDALOX15CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1562415-A1 COVER LAYERS TO PREVENT WEED GROWTH NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2005-08-17 EP disclosed
WO-2004047520-A1 COVER LAYERS TO PREVENT WEED GROWTH NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2004-06-10 WO disclosed