Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029704 | 0.93 | TACR1 (0.73) | TACR1 | |
| SCHEMBL4700386 | 0.88 | TACR1 (0.58) | TACR1 | |
| SCHEMBL6248371 | 0.88 | TACR1 (0.69) | TACR1 | |
| SCHEMBL6247332 | 0.88 | TACR1 (0.50) | TACR1 | |
| SCHEMBL6249957 | 0.88 | TACR1 (0.51) | TACR1 | |
| SCHEMBL4030869 | 0.85 | TACR1 (0.62) | TACR1 | |
| SCHEMBL6246152 | 0.84 | TACR1 (0.68) | TACR1 | |
| SCHEMBL6249954 | 0.84 | TACR1 (0.68) | TACR1 | |
| SCHEMBL4027893 | 0.83 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6271323 | 0.83 | TACR1 (0.58) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377558-B1 | [1,4]-DIAZEPANE-1-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS | GLAXO GROUP LTD (GB) | 2005-08-17 | — | — | EP | claimed |