Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 5/20 | 0.68 |
| ▸ | TARS1 | P26639 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12448217 | 0.84 | LARS1 (0.73) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3049869 | 0.81 | LARS1 (0.69) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL27943608 | 0.81 | LARS1 (0.65) | LARS1PTGS1 | |
| SCHEMBL28173973 | 0.81 | LARS1 (1.00) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL27943607 | 0.81 | LARS1 (0.65) | LARS1PTGS1 | |
| SCHEMBL18019131 | 0.81 | LARS1 (1.00) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL28591957 | 0.80 | LARS1 (0.97) | LARS1TARS1ALDH1A1GBA1 | |
| SCHEMBL15550141 | 0.80 | LARS1 (0.63) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15550140 | 0.80 | LARS1 (0.63) | LARS1TARS1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30483895 | 0.80 | LARS1 (0.63) | LARS1TARS1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562966-A1 | SUBSTITUTED 9A-N-[N'-(BENZENESULFONYL)CARBAMOYL-Y-AMINOPROPYL] AND 9a-N-[N'-(B-CYANEOTHYL)-N'-(BENZENESULFONYL)CARBAMOYL-Y-AMINOPROPYL] DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9A-AZA-9A-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9A-AZA-HOMOERITHRONOLIDE A | Pliva - Istrazivacki Institut d.o.o. (HR) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043984-A1 | SUBSTITUTED 9a-N-[N'-(BENZENESULFONYL)CARBAMOYL-Y-AMINOPROPYL]AND 9a-N-[N'-(B-CYANEOTHYL)-N'-(BENZENESULFONYL)CARBAMOYL-Y-AMINOPROPYL]DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9A-AZA-9A-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9A-AZA-HOMOERITHRONOLIDE A | PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2004-05-27 | — | — | WO | disclosed |