SCHEMBL6248474

SCHEMBL6248474

O=C(c1ccccc1)C(Br)(Br)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.54
CES2 O00748 2/20 0.46
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
SRC P12931 1/20 0.44
CYP1A2 P05177 1/20 0.43
PTPN1 P18031 1/20 0.43
GSK3B P49841 1/20 0.43
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
CYP3A4 P08684 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
POLB P06746 1/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28714764 0.86 KCNN4 (0.50) CES1CES2PTPN1TDP1CA2
SCHEMBL1799477 0.79 CES1 (0.64) CES1CES2TSHRALDH1A1DAO
SCHEMBL972914 0.79 CES1 (0.57) CES1CES2TSHRALDH1A1DAO
SCHEMBL1508202 0.78 CES1 (0.56) CES1CES2TSHRALDH1A1DAO
SCHEMBL1666976 0.78 CES1 (0.61) CES1CES2TSHRALDH1A1DAO
SCHEMBL15519395 0.78 CES1 (0.56) CES1CES2TSHRALDH1A1DAO
SCHEMBL14040482 0.77 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
SCHEMBL7595936 0.77 CES1 (0.55) CES1CES2TSHRALDH1A1DAO
SCHEMBL6333756 0.77 CYP1A2 (0.54) CES1CES2TSHRALDH1A1DAO
SCHEMBL7528244 0.77 CES1 (0.61) CES1CES2TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6730812-B2 BALL-MILLING AND SALT FORMATION, CATALYTIC REACTION IN ONE POT; CATALYST SELECTIVITY, EFFICIENCY, LOW TEMPERATURE, SIMPLIFICATION; FORMING UNSATURATED COMPOUNDS, 4-BROMOSTYRENE, ISOPROPENYLNAPHTHALENE/1-/ IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2004-05-04 US claimed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-5382504-A Negative photographic element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-17 US disclosed
US-5340712-A Tribormomethyl aminotriazines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-23 US disclosed
EP-0600587-A1 Photothermographic imaging materials and antifoggants therefor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-08 EP disclosed
EP-0306163-B1 PHOTOTHERMOGRAPHIC ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-08 EP disclosed
EP-0460825-A1 Photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-11 EP disclosed
EP-0460826-A1 Photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-11 EP disclosed
US-5041368-A Photosensitive silver halide emulsion containing an oxidizing agent, a reducing agent, a binder and a phthalazinone derivati ve MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-08-20 US disclosed
US-5028523-A Photosensitive Silver Halide Emulsion, Oxidizer, Reducing Agent, Hydrobromic Salts Of Nitrogen-Containing Heterocyclic Ring Compounds As An Antifoggant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-02 US disclosed
EP-0306163-A1 Photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4784939-A SILVER HALIDE, OXIDIZER, REDUCING AGENT, BENZOYL ALKANOIC ACID ANTIFOGGANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-15 US disclosed