Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | HRH1 | P35367 | 2/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL795619 | 0.98 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL19334368 | 0.91 | HRH1 (0.64) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| Oxalic Acid SCHEMBL9595892 | 0.90 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL6587582 | 0.87 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| Hydrochloric Acid SCHEMBL517553 | 0.86 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL9684268 | 0.85 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL24136460 | 0.83 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL226349 | 0.83 | HRH1 (0.78) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL20086419 | 0.83 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 | |
| SCHEMBL14704876 | 0.83 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662173-B2 | Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-05-26 | — | — | US | claimed |
| EP-3027602-B1 | NOVEL DERIVATIVES OF INDOLE AND PYRROLE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2018-06-13 | — | — | EP | claimed |
| US-20170342051-A1 | INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2017-11-30 | — | — | US | claimed |
| US-9765056-B2 | Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2017-09-19 | — | — | US | claimed |
| EP-3168217-A1 | NOVEL INDOLE AND PYRROLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2017-05-17 | — | — | EP | claimed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| EP-3027602-A1 | NOVEL DERIVATIVES OF INDOLE AND PYRROLE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2016-06-08 | — | — | EP | claimed |
| US-20160152599-A1 | INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2016-06-02 | — | — | US | claimed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |
| WO-2015011396-A1 | NOVEL DERIVATIVES OF INDOLE AND PYRROLE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2015-01-29 | — | — | WO | claimed |
| US-5183903-A | Urea fusion process for the synthesis of 3-phenoxy-1-azetidinecarboxamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| EP-0131435-B1 | PROCESS FOR PREPARING 3-PHENOXY-1-AZETIDINES AND CARBOXAMIDE DERIVATIVES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1987-10-07 | — | — | EP | claimed |
| US-4594189-A | Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives | A. H. ROBINS COMPANY, INC. (US) | 1986-06-10 | — | — | US | claimed |
| EP-0131435-A1 | Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-01-16 | — | — | EP | claimed |
| US-4379151-A | 3-Phenoxyazetidines for anorexigenic activity | A. H. ROBINS COMPANY, INC. (US) | 1983-04-05 | — | — | US | claimed |
| JP-5221963-A | — | — | None | — | — | JP | disclosed |
| EP-4635494-A2 | AMIDO HETEROAROMATIC COMPOUNDS | Astrazeneca AB (SE) | 2025-10-22 | — | — | EP | disclosed |
| US-4379151-A | 3-Phenoxyazetidines for anorexigenic activity | A. H. ROBINS COMPANY, INC. (US) | 1983-04-05 | — | — | US | disclosed |
| US-4226861-A | ANTICONVULSANTS | A. H. ROBINS COMPANY, INC. (US) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342051-A1 | INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RB1, IDO1, BCL2A1 | SLC6A4 3455/4885SLC6A2 4474/4885SLC6A3 3385/4885 |
| US-10662173-B2 | Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | RB1, IDO1, BCL2A1 | SLC6A4 3455/4885SLC6A2 4474/4885SLC6A3 3385/4885 |
| US-20160152599-A1 | INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IDO1, IDO2, NFATC1 | SLC6A4 3671/4885SLC6A2 4525/4885SLC6A3 3696/4885 |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | SLC6A4 4512/4885SLC6A2 4779/4885SLC6A3 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.