SCHEMBL6248685

SCHEMBL6248685

COC(=O)[C@H](C(=O)O)C(/C=C/c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.51
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.38
CNR2 P34972 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
GLA P06280 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054595 1.00 CYP1A2 (0.51) CYP1A2KMT2ATDP1ALDH1A1HTT
SCHEMBL6054594 1.00 CYP1A2 (0.51) CYP1A2KMT2ATDP1ALDH1A1HTT
SCHEMBL6248687 1.00 CYP1A2 (0.51) CYP1A2KMT2ATDP1ALDH1A1HTT
SCHEMBL5861097 0.94 KMT2A (0.50) CYP1A2KMT2ATDP1ALDH1A1CNR2
SCHEMBL11948863 0.94 KMT2A (0.50) CYP1A2KMT2ATDP1ALDH1A1CNR2
SCHEMBL13923800 0.94 KMT2A (0.50) CYP1A2KMT2ATDP1ALDH1A1CNR2
SCHEMBL5861107 0.94 KMT2A (0.50) CYP1A2KMT2ATDP1ALDH1A1CNR2
SCHEMBL10076671 0.90 CYP1A2 (0.46) CYP1A2KMT2ATDP1ALDH1A1CNR2
SCHEMBL25367803 0.86 CYP1A2 (0.62) CYP1A2TDP1ALDH1A1CNR2CYP2C19
SCHEMBL4089913 0.86 CYP1A2 (0.62) CYP1A2TDP1ALDH1A1CNR2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483276-B1 FERROCENYL LIGANDS AND THE USE THEREOF IN CATALYSIS DEGUSSA (DE) 2005-08-31 EP disclosed