Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317231 | 0.91 | PTGDR2 (0.68) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL6243833 | 0.89 | PTGDR2 (0.60) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL317068 | 0.81 | PTGDR2 (0.71) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL317473 | 0.80 | PTGDR2 (0.70) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL316954 | 0.79 | PTGDR2 (0.68) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL318332 | 0.78 | PTGDR2 (0.90) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL317878 | 0.78 | PTGDR2 (0.67) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL317320 | 0.77 | PTGDR2 (0.67) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL15017088 | 0.74 | PTGDR2 (0.62) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 | |
| SCHEMBL318388 | 0.73 | PTGDR2 (0.83) | PTGDR2PTGS1CYP2C9SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549634-A1 | NOVEL SUBSTITUTED INDOLES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003101981-A1 | NOVEL SUBSTITUTED INDOLES | ASTRAZENECA AB (SE) | 2003-12-11 | — | — | WO | disclosed |