Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127430 | 0.90 | CYP1A2 (0.52) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL7955051 | 0.90 | TSHR (0.52) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL1706721 | 0.88 | TSHR (0.50) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL7260921 | 0.88 | TSHR (0.50) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL7260925 | 0.88 | TSHR (0.51) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2846325 | 0.88 | NCEH1 (0.52) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL16042478 | 0.86 | TSHR (0.58) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL7653479 | 0.86 | TSHR (0.48) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL28807529 | 0.86 | NCEH1 (0.51) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2125551 | 0.86 | CYP1A2 (0.48) | TSHRCYP1A2CYP2A6ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1561762-A1 | PROCESS FOR PRODUCING PROPYLENE/ETHYLENE BLOCK COPOLYMER AND PROPYLENE/ETHYLENE BLOCK COPOLYMER | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2005-08-10 | — | — | EP | disclosed |