Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249265 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6249267 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6248508 | 0.88 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6248501 | 0.88 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6248505 | 0.88 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6250587 | 0.86 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6250584 | 0.86 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6250581 | 0.86 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6250535 | 0.84 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6251552 | 0.83 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157002-B1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-08-10 | — | — | EP | disclosed |