SCHEMBL624959

SCHEMBL624959

C=COC(=O)C1(CCC)CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL624447 0.89 CYP4F2 (0.40) CYP4F2CYP4A11TSHR
SCHEMBL8418182 0.87 CYP4F2 (0.42) CYP4F2CYP4A11TSHR
SCHEMBL5750098 0.86 CYP4F2 (0.45) CYP4F2CYP4A11TSHR
SCHEMBL181358 0.84 CYP4F2 (0.30) CYP4F2CYP4A11TSHR
SCHEMBL15063542 0.82 CYP4F2 (0.42) CYP4F2CYP4A11TSHR
Vinyl Chloride SCHEMBL5617462 0.82 CYP4F2 (0.42) CYP4F2CYP4A11TSHR
SCHEMBL28154962 0.81 CYP4F2 (0.44) CYP4F2CYP4A11TSHR
SCHEMBL8408805 0.80 CYP4F2 (0.46) CYP4F2CYP4A11TSHR
SCHEMBL13827636 0.75 CYP4F2 (0.56) CYP4F2CYP4A11TSHR
SCHEMBL3278382 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603555-B1 POLYMER FOAM TRISTANO PTY LTD (AU) 2017-02-15 EP claimed
US-9255197-B2 Polymer foam TRISTANO PTY LTD (AU) 2016-02-09 US claimed
US-20130196103-A1 POLYMER FOAM TRISTANO PTY LTD (AU) 2013-08-01 US claimed
EP-2603555-A1 POLYMER FOAM Tristano Pty Ltd (AU) 2013-06-19 EP claimed
WO-2012019244-A1 POLYMER FOAM TRISTANO PTY LTD (AU) 2012-02-16 WO claimed
CN-106674581-A Foaming body without residual formamide and preparation method thereof 良澔科技企业股份有限公司 2017-05-17 CN disclosed
EP-2603555-B1 POLYMER FOAM TRISTANO PTY LTD (AU) 2017-02-15 EP disclosed
US-9255197-B2 Polymer foam TRISTANO PTY LTD (AU) 2016-02-09 US disclosed
US-20130196103-A1 POLYMER FOAM TRISTANO PTY LTD (AU) 2013-08-01 US disclosed
EP-2603555-A1 POLYMER FOAM Tristano Pty Ltd (AU) 2013-06-19 EP disclosed
WO-2012019244-A1 POLYMER FOAM TRISTANO PTY LTD (AU) 2012-02-16 WO disclosed