⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386576 | 0.80 | — | — | |
| SCHEMBL386575 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL5142056 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL16892581 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL8102175 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL387549 | 0.78 | — | — | |
| SCHEMBL6672534 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL7462252 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL386565 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL385794 | 0.78 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282639-B1 | POLYAMIDE NUCLEIC ACID DERIVATIVES, AGENTS AND METHODS FOR PRODUCING THE SAME | AVENTIS PHARMA GMBH (DE) | 2005-08-17 | — | — | EP | claimed |
| US-6777544-B2 | Polyamide nucleic acid derivatives and agents and processes for preparing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-17 | — | — | US | claimed |
| US-20030022172-A1 | Polyamide nucleic acid derivatives and agents and processes for preparing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-01-30 | — | — | US | claimed |