Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224867 | 0.95 | TAAR1 (0.52) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6704719 | 0.87 | MCHR1 (0.66) | MCHR1CHRM1HTR2ACYP2D6CYP1A2 | |
| SCHEMBL6705810 | 0.82 | MCHR1 (0.67) | MCHR1CHRM1HTR2ACYP2D6CYP1A2 | |
| SCHEMBL6228545 | 0.81 | MCHR1 (0.70) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6223485 | 0.79 | MCHR1 (0.72) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6226448 | 0.77 | POLB (0.56) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6226422 | 0.76 | TAAR1 (0.54) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6224443 | 0.76 | TAAR1 (0.51) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6228341 | 0.75 | TAAR1 (0.53) | TAAR1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6226417 | 0.72 | TAAR1 (0.49) | TAAR1NPC1RAB9ALIPEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534689-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004024702-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-25 | — | — | WO | disclosed |