Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.42 |
| ▸ | RARG | P13631 | 15/20 | 0.42 |
| ▸ | RARA | P10276 | 15/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491751 | 0.77 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4503989 | 0.73 | RARB (0.66) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4497657 | 0.72 | RARB (0.48) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4497873 | 0.72 | RARB (0.41) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4509109 | 0.72 | RARB (0.39) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4506849 | 0.72 | RARB (0.46) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4506857 | 0.72 | RARB (0.46) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4494185 | 0.72 | RARB (0.44) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4508557 | 0.72 | RARB (0.44) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL4494180 | 0.72 | RARB (0.44) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565433-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-08-24 | — | — | EP | claimed |
| WO-2004046096-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT,S.N.C. (FR) | 2004-06-03 | — | — | WO | claimed |
| EP-1565433-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046096-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT,S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |