Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60939 | 0.87 | KMT2A (0.71) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL810891 | 0.84 | KDM4E (0.44) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL31734506 | 0.77 | KMT2A (0.66) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL1456317 | 0.75 | KMT2A (0.71) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL3871978 | 0.75 | KMT2A (0.62) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL19954629 | 0.74 | SMN1; SMN2 (0.47) | KMT2AKDM4EMEN1XDHSMN1; SMN2 | |
| SCHEMBL6205563 | 0.73 | KMT2A (1.00) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL3876365 | 0.73 | KMT2A (0.73) | KMT2AKDM4EMEN1XDHSMN1; SMN2 | |
| SCHEMBL6071143 | 0.73 | KMT2A (0.69) | KMT2AKDM4EMEN1XDHNPC1 | |
| SCHEMBL12795372 | 0.73 | KMT2A (0.74) | KMT2AKDM4EMEN1XDHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499614-A4 | ADENOSINE A3 RECEPTOR MODULATORS | KING PHARMACEUTICALS RES & DEV (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1499614-A1 | ADENOSINE A3 RECEPTOR MODULATORS | King Pharmaceuticals Research and Development Inc. (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003095457-A1 | ADENOSINE A3 RECEPTOR MODULATORS | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
| WO-2000015231-A9 | ADENOSINE A3 RECEPTOR MODULATORS | MEDCO RES INC (US) | 2000-08-17 | — | — | WO | disclosed |