Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 19/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250969 | 1.00 | SLC6A4 (0.83) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6250975 | 1.00 | SLC6A4 (0.83) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6244447 | 0.91 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6244442 | 0.91 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6244437 | 0.91 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6250558 | 0.90 | SLC6A2 (0.98) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6944429 | 0.87 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6250495 | 0.84 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6250489 | 0.84 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13409764 | 0.84 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157002-B1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-08-10 | — | — | EP | disclosed |
| EP-1157002-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000051972-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |