Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1665368 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL20617 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL11012463 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL344632 | 1.00 | — | — | |
| Acetic Acid SCHEMBL9098767 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL3634629 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL8527135 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL1058300 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL3420431 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL220259 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227885-B1 | PROCESS FOR THE PREPARATION OR REACTIVATION OF CARBON MONOXIDE HYDROGENATION CATALYSTS | EXXONMOBIL RES & ENG CO (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20040105156-A1 | Coated article | KAYANOKI HISAYUKI (JP) | 2004-06-03 | — | — | US | disclosed |
| US-6703131-B1 | COATED PLASTIC LENS HAVING A TITANIUM OXIDE-CONTAINING RESIN COAT LAYER | NIPPON ARC CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-6331574-B1 | PRODUCING HYDROCARBONS USING CATALYST WITH INCREASED ACTIVITY FORMED BY REMOVING SOME OF METAL ATOMS WITH CHELATING COMPOUND CONTAINING NITROGEN OR OXYGEN AND HAVING DENTICITY OF AT LEAST TWO | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2001-12-18 | — | — | US | disclosed |
| EP-1162245-A1 | COATED ARTICLE | NIPPON ARC CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-20010047041-A1 | Process for the preparation of high activity carbon monoxide hydrogenation catalysts; the catalyst compositions, use of the catalysts for conducting such reactions, and the products of such reactions | LAPIDUS ABERT L VOVOCH (RU) | 2001-11-29 | — | — | US | disclosed |
| US-6221820-B1 | Granular component containing alkylaminotriazole for use in machine dishwashing detergents | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-24 | — | — | US | disclosed |
| EP-0602125-A1 | QUINAZOLINE DERIVATIVES AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005035-A1 | QUINAZOLINE DERIVATIVES AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-18 | — | — | WO | disclosed |
| US-5021381-A | Syndiotactic 1,2-polybutadiene latex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0357535-A1 | Syndiotactic 1,2-polybutadiene latex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4902741-A | Syndiotactic 1,2-polybutadiene latex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047041-A1 | Process for the preparation of high activity carbon monoxide hydrogenation catalysts; the catalyst compositions, use of the catalysts for conducting such reactions, and the products of such reactions | KAT5, TAF5, C9 | FFAR3 4795/4885LCK 833/4885FYN 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.