SCHEMBL625150

SCHEMBL625150

O=C1c2ccccc2C(=O)c2c(Nc3ccccc3)cccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.62
MAPK1 P28482 6/20 0.62
SMN1; SMN2 Q16637 6/20 0.62
L3MBTL1 Q9Y468 6/20 0.62
RAB9A P51151 4/20 0.62
TDP1 Q9NUW8 2/20 0.62
EGFR P00533 2/20 0.62
PABPC1 P11940 1/20 0.62
CYP1A2 P05177 3/20 0.56
MAOA P21397 1/20 0.56
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
GNG2 P59768 1/20 0.52
GNB1 P62873 1/20 0.52
HIF1A Q16665 1/20 0.52
P2RY2 P41231 3/20 0.49
P2RY4 P51582 3/20 0.49
P2RY12 Q9H244 3/20 0.49
CDK2 P24941 2/20 0.49
P2RY1 P47900 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11600205 0.96 MAPT (0.59) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL2612577 0.96 MAPT (0.56) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL11604892 0.94 MAPT (0.55) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL11606051 0.91 MAPT (0.51) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL11659244 0.90 MAPT (0.56) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL21635984 0.89 CYP1A2 (0.59) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL42481 0.88 MAPT (0.71) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL11306687 0.88 MAPT (0.71) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL29438168 0.88 MAPT (0.71) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A
SCHEMBL14669292 0.88 MAPT (0.49) MAPTMAPK1SMN1; SMN2L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138302-A Preparation method of 1- (phenylamino) anthraquinone 南京金浩医药科技有限公司 2020-05-12 CN claimed
CN-105601965-B A kind of method for preparing polyurethane-poly-isocyanurate film functionally gradient material (FGM) 盐城工学院 2018-05-18 CN claimed
CN-103885233-B Method for preparing color polymer dispersed liquid crystal films 北京众智同辉科技股份有限公司 2017-05-24 CN claimed
CN-105601965-A Preparation method of polyurethane-polyisocyanurate thin-film graded material YANCHENG INST TECHNOLOGY 2016-05-25 CN claimed
CN-104004172-A Dehydration treatment process of aliphatic polyester degradable polymer before molding TIANJIN DONGNANHENGSHENG MEDICAL TECHNOLOGIES CO LTD 2014-08-27 CN claimed
CN-103885233-A Method for preparing color polymer dispersed liquid crystal films BEIJING ALL BRILLIANT TECHNOLOGY CO LTD 2014-06-25 CN claimed
CN-1693404-A Compositions for use in electronics devices NAT STARCH CHEM INVEST (US) 2005-11-09 CN claimed
EP-0284568-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-29 EP claimed
US-4929719-A Fiber-reactive dyes containing an aniline radical which carries two different vinylsulfonyl moieties CIBA-GEIGY CORPORATION (US) 1990-05-29 US claimed
EP-0144766-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-10-05 EP claimed
EP-0284568-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1988-09-28 EP claimed
EP-0159292-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-01-07 EP claimed
EP-0103986-B1 ORGANIC ANTHRAQUINONE DYES CONTAINING SILANE GROUPS,PIGMENTS AND PROCESS FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-04-08 EP claimed
EP-0159292-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-23 EP claimed
EP-0144766-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP claimed
US-4436852-A Process for the coloration of linear polyesters in the melt with perylenetetracarboxylic acid bis-methylimide CIBA-GEIGY CORPORATION (US) 1984-03-13 US claimed
US-4369038-A Transfer-printing paper, its manufacture and uses CIBA-GEIGY LTD. (CH) 1983-01-18 US claimed
EP-0020292-A1 Auxiliary supports for transfer printing and thermographic printing process using these supports SUBLISTATIC HOLDING S.A. (CH) 1980-12-10 EP claimed
JP-58217579-A None JP disclosed
US-3975410-A Process for the manufacture of halogen-containing anthraquinoidal compounds, their use and new halogen-containing anthraquinoidal compounds CIBA-GEIGY CORPORATION (US) 1976-08-17 US disclosed