Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.68 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | F11 | P03951 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | HMGCR | P04035 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15814640 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL14356268 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL17326916 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL14037294 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL4875707 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL14011212 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL6252668 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL12154605 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL19090430 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 | |
| SCHEMBL15814641 | 1.00 | PTPN1 (0.68) | PTPN1PTPN2PTPN11F11USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572709-A3 | USE OF NUCLEOSIDE COMPOUNDS FOR NONSENSE SUPPRESSION AND THE TREATMENT OF GENETIC DISEASES | PTC Therapeutics, Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| EP-1572709-A2 | USE OF NUCLEOSIDE COMPOUNDS FOR NONSENSE SUPPRESSION AND THE TREATMENT OF GENETIC DISEASES | PTC Therapeutics, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004009610-A2 | USE OF NUCLEOSIDE COMPOUNDS FOR NONSENSE SUPPRESSION AND THE TREATMENT OF GENETIC DISEASES | PTC THERAPEUTICS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |