Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734308 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL3209613 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL6079072 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL3209615 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL4483433 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL18603363 | 0.98 | SLC6A2 (0.41) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL334961 | 0.98 | SLC6A2 (0.44) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL4479086 | 0.98 | SLC6A2 (0.44) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL335654 | 0.98 | SLC6A2 (0.44) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL4479090 | 0.98 | SLC6A2 (0.44) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054180-A1 | ANTIAMYLOID PHENYLSULFONAMIDES: N-CYCLOALKYLCARBOXAMIDES DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |