Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL7728593 | 1.00 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL1415387 | 1.00 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL1441830 | 0.91 | KDM4A (0.36) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL2120547 | 0.90 | KDM4A (0.38) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL6421376 | 0.90 | KDM4A (0.38) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL3157 | 0.90 | — | — | |
| Purine SCHEMBL29456595 | 0.90 | — | — | |
| Purine SCHEMBL20520352 | 0.88 | KDM4A (0.39) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL6438162 | 0.88 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM4CKDM5B | |
| Purine SCHEMBL1389668 | 0.88 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114561429-A | Treatment method for inhibiting HBV surface antigen based on base editing ATG initiation codon | 绍兴市妇幼保健院 | 2022-05-31 | — | — | CN | claimed |
| CN-114561392-A | Method for removing HBV e antigen by closing target gene based on base editing technology | 绍兴市妇幼保健院 | 2022-05-31 | — | — | CN | claimed |
| CN-113409882-A | Method for gene therapy by inducing proton transfer of pyrimidine or purine to change its pairing property | 薛晋杰 | 2021-09-17 | — | — | CN | claimed |
| CN-112182497-B | Biological sequence-based negative sequence pattern similarity analysis method, realization system and medium | 齐鲁工业大学 | 2021-04-27 | — | — | CN | claimed |
| CN-112182497-A | Biological sequence-based negative sequence pattern similarity analysis method, realization system and medium | 齐鲁工业大学 | 2021-01-05 | — | — | CN | claimed |
| EP-3001814-A2 | XANTHINE OXIDASE INHIBITOR FORMULATIONS | Allen, Davidoff (CA) | 2016-04-06 | — | — | EP | claimed |
| US-20160038595-A1 | XANTHINE OXIDASE INHIBITOR FORMULATIONS | XORTX THERAPEUTICS, INC. (CA) | 2016-02-11 | — | — | US | claimed |
| WO-2014140868-A2 | XANTHINE OXIDASE INHIBITOR FORMULATIONS | ALLEN DAVIDOFF (CA) | 2014-09-18 | — | — | WO | claimed |
| CN-102286551-B | Fermentation process regulation and control method of fumaric acid radical-producing mould | NANJING UNIVERSITY OF TECHNOLOGY | 2014-05-21 | — | — | CN | claimed |
| EP-1436415-B1 | NUCLEIC ACID TRIPLEX AND QUADRUPLEX FORMATION | INGENEUS CORP (BB) | 2012-08-22 | — | — | EP | claimed |
| US-6590093-B1 | Modified RNA which can be easily handled and analyzed with minimal degradation; stability; can use in synthesis of polymers containing RNA nucleotides | DHARMACON, INC. | 2003-07-08 | — | — | US | claimed |
| US-6362322-B1 | PREPARING A PYR*PUR:PYR RNA*DNA:RNA TRIPLEX; SEPARATING A WATSON-CRICK PAIRED PYRIMIDINE STRAND BY HEATING TO ABOVE THE MELTING TRANSITION FOR THE WATSON-CRICK PAIRED STRAND; AND REMOVING A PYR*PUR HOOGSTEEN DUPLEX WHICH AS STABILITY TO BOND | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-03-26 | — | — | US | claimed |
| WO-2001005937-A2 | CONVERSION OF A WATSON-CRICK DNA TO A HOOGSTEEN-PAIRED DUPLEX | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 2001-01-25 | — | — | WO | claimed |
| CN-1048400-C | Vitamin micro-element purine pyrimidine dinucleotide nutrient product and producing method | YAN HUAIWEI (CN) | 2000-01-19 | — | — | CN | claimed |
| EP-0285057-B1 | Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same | ENZO BIOCHEM INC (US) | 1995-03-01 | — | — | EP | claimed |
| CN-1097598-A | Vitamin micro-element purine pyrimidine dinucleotide nutrient product and manufacture method | YAN HUAIWEI (CN) | 1995-01-25 | — | — | CN | claimed |
| EP-0200057-B1 | DIAGNOSTIC REAGENT, KIT AND METHOD EMPLOYING POLYNUCLEOTIDE DISPLACEMENT, SEPARATION, ENZYMATIC CLEAVAGE AND ADENOSINE PHOSPHATE DETECTION | AlliedSignal Inc. (US) | 1990-11-22 | — | — | EP | claimed |
| EP-0286642-A4 | DISPLACEMENT POLYNUCLEOTIDE METHOD AND REAGENT COMPLEX. | GENETICS INST (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0286642-A1 | DISPLACEMENT POLYNUCLEOTIDE METHOD AND REAGENT COMPLEX | GENETICS INSTITUTE, INC. (US) | 1988-10-19 | — | — | EP | claimed |
| WO-1987003911-A1 | DISPLACEMENT POLYNUCLEOTIDE METHOD AND REAGENT COMPLEX | GENETICS INSTITUTE, INC. (US) | 1987-07-02 | — | — | WO | claimed |