Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226122 | 1.00 | HIF1A (0.48) | HIF1AHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL6229612 | 1.00 | HIF1A (0.48) | HIF1AHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL6226597 | 1.00 | HIF1A (0.48) | HIF1AHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL6230235 | 1.00 | HIF1A (0.48) | HIF1AHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL6226964 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6226965 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6226968 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6267799 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6226963 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6228364 | 0.92 | HIF1A (0.50) | HIF1AHPGDMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026151-B1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1026151-A1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |