Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 18/20 | 0.65 |
| ▸ | GRPR | P30550 | 16/20 | 0.65 |
| ▸ | FPR1 | P21462 | 3/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250081 | 0.93 | NMBR (0.66) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252606 | 0.91 | NMBR (0.70) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6250567 | 0.91 | NMBR (0.65) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6251905 | 0.91 | NMBR (0.65) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6253658 | 0.90 | NMBR (0.73) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6249989 | 0.90 | NMBR (0.70) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252001 | 0.89 | NMBR (0.77) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252267 | 0.89 | NMBR (0.69) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6251857 | 0.89 | NMBR (0.69) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6250037 | 0.89 | NMBR (0.63) | NMBRGRPRFPR1AGTR1GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | claimed |