Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374060 | 0.91 | LTB4R2 (0.49) | LTB4R2PLK1AGTR1 | |
| SCHEMBL5358339 | 0.81 | LTB4R2 (0.44) | LTB4R2RARBRARARARG | |
| SCHEMBL5360863 | 0.77 | AOC3 (0.48) | LTB4R2 | |
| SCHEMBL5374067 | 0.76 | LTB4R2 (0.42) | LTB4R2MEN1RECQLBLMKMT2A | |
| SCHEMBL5355948 | 0.76 | AOC3 (0.49) | LTB4R2 | |
| SCHEMBL6251973 | 0.76 | ABCC1 (0.44) | LTB4R2MEN1RECQLBLMKMT2A | |
| SCHEMBL6256861 | 0.73 | NPC1 (0.38) | — | |
| SCHEMBL4248139 | 0.73 | PLK1 (0.72) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL6483217 | 0.72 | PLK1 (0.70) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL3439045 | 0.72 | PPARG (0.48) | MEN1BLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |