Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967997 | 0.83 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HPGDEPHX2 | |
| SCHEMBL22338022 | 0.81 | CHRM2 (0.51) | CHRM2CHRM1CHRM3HPGDEPHX2 | |
| SCHEMBL31249588 | 0.81 | CHRM2 (0.51) | CHRM2CHRM1CHRM3HPGDEPHX2 | |
| SCHEMBL6256937 | 0.79 | CHRM2 (0.35) | CHRM2CHRM1CHRM3DPP4CTSK | |
| SCHEMBL23245696 | 0.79 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HPGDCTSK | |
| SCHEMBL25712548 | 0.79 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HPGDCTSK | |
| SCHEMBL30968082 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDCTSK | |
| SCHEMBL16115131 | 0.72 | CHRM2 (0.66) | CHRM2CHRM1CHRM3HPGDDPP4 | |
| SCHEMBL16135448 | 0.72 | CHRM2 (0.66) | CHRM2CHRM1CHRM3HPGDDPP4 | |
| SCHEMBL796116 | 0.72 | CHRM2 (0.66) | CHRM2CHRM1CHRM3HPGDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058317-A1 | GLYCINE TRANSPORTER-1 INHIBIRORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |