Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233514 | 0.89 | F10 (0.50) | F10ITGB3ITGA2BSMN1; SMN2F2 | |
| SCHEMBL6239834 | 0.86 | F10 (0.48) | F10ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL6239827 | 0.86 | F10 (0.48) | F10ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL6237006 | 0.85 | F10 (0.49) | F10ITGB3ITGA2BF2 | |
| SCHEMBL6233491 | 0.84 | F10 (0.55) | F10ITGB3ITGA2BF2 | |
| SCHEMBL6237033 | 0.84 | F10 (0.48) | F10ITGB3ITGA2BSMN1; SMN2F2 | |
| SCHEMBL6237040 | 0.84 | F10 (0.48) | F10ITGB3ITGA2BSMN1; SMN2F2 | |
| SCHEMBL6233749 | 0.83 | F10 (0.53) | F10ITGB3ITGA2BF2 | |
| SCHEMBL6257514 | 0.82 | F10 (0.47) | F10ITGB3ITGA2BMAPTSMN1; SMN2 | |
| SCHEMBL6239516 | 0.82 | F10 (0.47) | F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | disclosed |