SCHEMBL6256428

SCHEMBL6256428

Cc1occc1[S]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115390 0.69
SCHEMBL8529510 0.69
SCHEMBL31447708 0.69 KDM4E (0.39)
SCHEMBL8014964 0.67
Hydrochloric Acid SCHEMBL29135193 0.67
SCHEMBL2968764 0.66
SCHEMBL6258941 0.65
SCHEMBL5678348 0.65
SCHEMBL5312705 0.65
SCHEMBL11522722 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090557-B1 Savoury flavour comprising 2-methyl-furan -3-thiol and/or a derivative and methylenedithiol and/or a derivative QUEST INT (NL) 2005-09-28 EP claimed
US-6716468-B1 MEAT FLAVORED FOODSTUFF COMPRISING COMBINATION OF AT LEAST ONE COMPOUND WITH (HYDROGENATED) 2-METHYL-3-FURYL-THIO MOIETY AND AT LEAST ONE COMPOUND WITH METHYLTHIO MOIETY QUEST INTERNATIONAL B.V. (NL) 2004-04-06 US claimed
EP-1090557-A1 Savoury flavour comprising 2-methyl-furan -3-thiol and/or a derivative and methylenedithiol and/or a derivative QUEST INTERNATIONAL B.V. (NL) 2001-04-11 EP claimed
EP-1090557-B1 Savoury flavour comprising 2-methyl-furan -3-thiol and/or a derivative and methylenedithiol and/or a derivative QUEST INT (NL) 2005-09-28 EP disclosed
US-6716468-B1 MEAT FLAVORED FOODSTUFF COMPRISING COMBINATION OF AT LEAST ONE COMPOUND WITH (HYDROGENATED) 2-METHYL-3-FURYL-THIO MOIETY AND AT LEAST ONE COMPOUND WITH METHYLTHIO MOIETY QUEST INTERNATIONAL B.V. (NL) 2004-04-06 US disclosed
US-20040058957-A1 Benzothiophene derivatives and herbicidal compositions containing the same IDEMITSU KOSAN CO., LTD. (JP) 2004-03-25 US disclosed
EP-1090557-A1 Savoury flavour comprising 2-methyl-furan -3-thiol and/or a derivative and methylenedithiol and/or a derivative QUEST INTERNATIONAL B.V. (NL) 2001-04-11 EP disclosed
US-6156761-A Substituted tetralone derivatives for enhancing cognition MERCK SHARPE & DOHME LIMITED (GB) 2000-12-05 US disclosed
US-4626599-A Dithioethers of 2-phenyl-2-alkenals and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-12-02 US disclosed
US-4623538-A CHEWING GUM, TOOTHPASTE, MEDICINAL PRODUCTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-11-18 US disclosed
US-4571344-A Flavoring with dithioethers of 2-phenyl-2-alkenals INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-02-18 US disclosed
US-4481224-A POSSIBLE REPLACEMENT FOR MONOSODIUM GLUTAMATE IN FOODS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-11-06 US disclosed