Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.78 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.78 |
| ▸ | PDE4A | P27815 | 11/20 | 0.78 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887652 | 1.00 | PDE7B (0.85) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5564655 | 0.92 | PDE7B (1.00) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5564653 | 0.92 | PDE7B (1.00) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5564651 | 0.92 | PDE7B (1.00) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2886831 | 0.89 | PDE4D (0.74) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6467291 | 0.89 | PDE4D (0.74) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2887808 | 0.89 | PDE7B (0.73) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5528256 | 0.89 | PDE7B (0.73) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL4018156 | 0.88 | PDE4D (0.73) | PDE7BPDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7142486 | 0.88 | PDE4B (1.00) | PDE7BPDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023253-A1 | USE OF PDE4 INHIBITORS FOR THE TREATMENT OF DIABETES MELLITUS | ALTANA PHARMA AG (DE) | 2005-03-17 | — | — | WO | claimed |
| US-6953853-B2 | Phospholipase inhbitors; antiinflammatory agents; respiratory system disorders | ALTANA PHARMA AG (DE) | 2005-10-11 | — | — | US | disclosed |