Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.52 |
| ▸ | FNTB | P49356 | 5/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341035 | 1.00 | FNTA (0.52) | FNTAFNTBPGGT1BMAPK1ALDH1A1 | |
| SCHEMBL5967013 | 0.95 | FNTA (0.53) | FNTAFNTBPGGT1BMAPK1ALDH1A1 | |
| SCHEMBL3346474 | 0.86 | HTT (0.58) | ALDH1A1USP2 | |
| SCHEMBL2976475 | 0.84 | PSEN1 (0.57) | — | |
| SCHEMBL1793314 | 0.84 | PSEN1 (0.57) | — | |
| SCHEMBL2331099 | 0.83 | FNTA (0.61) | FNTAFNTBPGGT1BMAPK1ALDH1A1 | |
| SCHEMBL2331097 | 0.83 | FNTA (0.61) | FNTAFNTBPGGT1BMAPK1ALDH1A1 | |
| SCHEMBL4056322 | 0.82 | CNR2 (0.50) | — | |
| SCHEMBL5210931 | 0.81 | TDP1 (0.50) | ALDH1A1 | |
| SCHEMBL9358936 | 0.81 | NPSR1 (0.55) | FNTAFNTBPGGT1BMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554250-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031154-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-04-15 | — | — | WO | disclosed |