SCHEMBL62569

SCHEMBL62569

[N]c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801704 1.00
Dipyridyl SCHEMBL16026539 0.71 KDM4E (0.93)
SCHEMBL6750082 0.69
Hydrochloric Acid SCHEMBL8046759 0.69
Dipyridyl SCHEMBL4196776 0.69 KDM4E (0.88)
Dipyridyl SCHEMBL29351528 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL3711450 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL29907716 0.67 KDM4E (1.00)
Dipyridyl SCHEMBL5922 0.67 KDM4E (1.00)
SCHEMBL27893095 0.67 KDM4E (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901280-B MrgprX2 antagonists and uses thereof 德米拉公司 2025-05-27 CN claimed
CN-118406068-A Cadmium complex semiconductor crystal material with photocurrent response and preparation method and application thereof 宁波大学 2024-07-30 CN claimed
CN-118290630-A Homo-polymerization and copolymerization reaction of acrylic esters and polar olefins participated by diamino or monoaminophosphine 青岛大学 2024-07-05 CN claimed
CN-117567766-A Porous crystal material for adsorbing gas molecules and preparation method and application thereof 宁波大学 2024-02-20 CN claimed
CN-116813929-A Solvent-response sensor crystal material and preparation method thereof 宁波大学 2023-09-29 CN claimed
CN-113015617-B Carbon nanofiber and method for producing the same Cence公司 2023-07-04 CN claimed
US-20230027929-A1 MrgprX2 Antagonists and Uses Thereof DERMIRA, INC. 2023-01-26 US claimed
EP-4054570-A1 MRGPRX2 ANTAGONISTS AND USES THEREOF Dermira, Inc (US) 2022-09-14 EP claimed
CN-114901280-A MrgprX2 antagonists and uses thereof 德米拉公司 2022-08-12 CN claimed
WO-2022152853-A1 ANTAGONISTS OF MRGX2 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2022-07-21 WO claimed
EP-0424525-A1 NOVEL AMINES AND THEIR USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-02 EP claimed
US-4631297-A QUATERNARY AMMONIUM SALTS OF SILANES AND CATALYSTS SURFACTANTS AND MICROBIOCIDE; URETHANE FOAMS DOW CORNING CORPORATION (US) 1986-12-23 US claimed
US-4564456-A ORGANOSILYLACKYLAMMONIUM SALT DOW CORNING CORPORATION (US) 1986-01-14 US claimed
EP-0076643-B1 PROCESSES FOR PREPARING PIROXICAM AND INTERMEDIATES LEADING THERETO PFIZER INC. (US) 1985-02-20 EP claimed
US-4483982-A REACTING N-METHYLSACCHARIN WITH (N-2-PYRIDYL) HALOACETAMIDES OR ALKYLACETATES PFIZER INC. (US) 1984-11-20 US claimed
EP-0083901-A1 Preparation of thionamide compounds by sulfuration of imines ASHLAND OIL, INC. (US) 1983-07-20 EP claimed
EP-0076643-A1 Processes for preparing piroxicam and intermediates leading thereto PFIZER INC. (US) 1983-04-13 EP claimed
US-4376767-A ANTIBIOTICS AND PHARMACEUTICALS MERCK & CO., INC. (US) 1983-03-15 US claimed
US-4348523-A OIL ADDITIVES ASHLAND OIL, INC. (US) 1982-09-07 US claimed
US-3966741-A Process for the preparation of substituted or unsubstituted 4-pyridylthioacetic acid OCE-ANDENO B.V. (NL) 1976-06-29 US claimed